INDIGENOUS MEDICINAL PLANTS POTENTIAL AS ANTIMYCOTIC DRUG TO CURE FOOT FUNGAL DISEASES AND PRODUCTION OF ITS COMMERCIALABLE HERBAL PRODUCT TO FACILITATE LOCAL COMMUNITIES OF DISTRICT BHIMBER, AZAD KASHMIR
In present research project a comprehensive investigation was conducted to explore the contaminants in herbal drugs and their by-products applying by different methodologies and techniques. In this research, indigenous medicinal plants of District Bhimber which has been used by local communities since long past; were selected and tested for their medicinal potential and plethora of contaminations by unconscious under/or deliberate adulteration by similar types of phenotypic plants. Four mycop
athogens (Microsporum canis, Candida albicans, Trichophyton mannum) but in this research, the major mycopathogen was Candida albicans and four plants (Azadirachta indica, Eucalyptus citridora, Allium sativum, and Mentha piperita) were used for the study analysis of fungal disease and their phytotherapist treatment in district Bhimber. In this analysis, firstly, ethnobotanical approach consisting of survey was used for exploring indigenous medicinal knowledge of these taxa and all these plants were collected for herbaria preparation and lab analysis. Secondly, herbarium and fresh specimens were used to study morphological description to study plants for identification purpose. The values were measured and data was statistically analyzed throughout research of different medicinal plant's properties against the infection Candida albicans. Based on these results, it is existed that the Minimal Inhibitory Concentration (MIC) diverges amongst extracts which differs significantly from the control. Overall, the presence of terpenoids in Azadirachta indica (neem) plant extract was estimated to have the greatest minimum inhibitory concentration (MIC), which inhibits fungal hyphae growth in Candida albicans illness. Azadirachta indica consumes best antifungal activity that devastates progression of fungus after comparing the antifungal activity of extracts from four plants against foot fungal disease caused by Candida albicans, Trichophyton mannum, a dermophytic fungal pathogen, was utilized to assess and record the impact of extracts from four medicinal herbs against Ringworm. In comparison to the other three therapeutic plants, Eucalyptus citridora extract was thought to have better benefits. Eucalyptus contains a molecule called 1,8-cineole, which inhibits fungus development. However, because Neem oil includes Quercetin and sitosterol, it was assessed that it performed better against Candida albicans in all four extracts to cure Athlete's foot illness. In this study, it is concluded that ethanol solvent gets better results and minimum inhibitory concentration (MIC) value differ in different plant extract.