HYPOGLYCEMIC ACTIVITY OF CANNABIS SATIVA L. ON ALOXAN INDUCED DIABETES
Abstract
Abstract
Diabetes mellitus is commonly referred to as "diabetes." It's a metabolic condition caused by a mix of inherited and environmental factors that leads to unusually high blood sugar levels. The body's blood glucose level is regulated by a complicated interaction of various substances and hormones. For this purpose rabbits were used as experimental animals, as all mammals have same characteristics so, rabbits were used. The results of researc
h proved significant reduction in sugar level on 15 days of trials. Results depicted that T2-group treated with 1g of leaf extract from Cannabis showed maximum decrease in blood glucose level i.e; 170±1.15 mg/dl. The body weight was also decreased in T2-group i.e; 1.15±0.01 kg, as compared to other groups. . Serum insulin levels improved in both treatment groups, although they improved the most in the T2-group on the 15th day of treatment, reaching 5.940.01 pmol/L. The researchers discovered that an ethanolic extract of Cannabis sativa L. had a significant anti-hyperglycemic potential. (less than allopathic medicines) which can be used to cure in diabetes mellitus, thus justifying that the novel allopathic and herbal drug can be produced and optimized from this plant, from AJK territory. The present investigation showed that the Cannabis sativa L. leaves extract can be used efficiently in diabetes.